Naturopathic Approach to Endometriosis: Top Supplements

Healthy View

Written by: Dr. Madison Sangster-Newbery, ND, Naturopathic Doctor, Adelaide Health Clinic & Sport Medicine Clinic 

Endometriosis is a condition where tissue resembling the uterine lining grows outside the uterus. These misplaced tissues respond to hormonal changes, leading to inflammation, pain, immune dysfunction, and sometimes infertility. Many people feel frustrated with treatment options, so looking at a holistic approach - particularly one that includes targeted supplementation - can offer extra support and compliment conventional care. Below are my top supplement recommendations, along with some naturopathic insights on managing endometriosis. 

Addressing the Whole Person 

Naturopathic medicine focuses on treating the root causes of health concerns. For endometriosis, this means looking at hormones, liver function, gut health, inflammation, and stress levels. While supplements can be powerful, everyone’s situation is unique. Adjusting diet, managing stress, and getting regular exercise are also key pieces of the puzzle. 

Ginger: A Natural Pain Reliever 

Ginger is a favourite remedy for menstrual pain. Research shows that it can rival nonsteroidal anti-inflammatory drugs (like ibuprofen) in reducing endometriosis-related pain. But that’s not all - ginger may also soothe digestive issues, which often flare up around menstruation. Taking ginger in a concentrated supplement form ensures you’re getting a therapeutic dose without having to consume large amounts of the fresh root. 

Naturopathic Tip: 

• Combine ginger supplements with warm compresses on the lower abdomen. The added heat can help relax tight muscles and further relieve pain. 

Melatonin: More Than Just Sleep Support 

Melatonin is well-known for its role in sleep regulation, but it also offers powerful antioxidant benefits. Studies indicate it may significantly reduce endometriosis pain and lessen the need for pain medications. Animal research further suggests melatonin might help shrink and slow the growth of endometrial lesions. Taking it before bed could improve both sleep quality and pain management - two critical factors when dealing with endometriosis. 

Naturopathic Tip: 

• Practice good sleep hygiene by sticking to a consistent sleep and wake times, and turning off electronic devices well before bedtime. This enhances melatonin’s natural production and makes supplementation more effective. 

N-Acetyl Cysteine (NAC): The Multi-Purpose Tool 

NAC is derived from the amino acid L-cysteine and is particularly useful for its anti-inflammatory and antioxidant properties. One of its key benefits is supporting the liver, which helps process and detoxify excess hormones - important if you have endometriosis. It may also boost immune function. Research shows that NAC supplementation may reduce the size of endometrial lesions and help lessen pain. 

Naturopathic Tip: 

• Another way to support the liver and detoxification is to make sure that you are having regular bowel movements. Staying hydrating and eating lots of fibre can help you get consistent and comfortable bowel movements.  

Resveratrol: A Potent Antioxidant Powerhouse 

Resveratrol, found in the skins of grapes and certain berries, is renowned for its anti-inflammatory and antioxidant effects. Studies suggest that it may aid in limiting new blood vessel formation in endometrial lesions and help trigger apoptosis (cell death) in problematic tissue. While resveratrol occurs naturally in red wine, you won’t get a therapeutic dose from a glass or two. In fact, alcohol can aggravate endometriosis symptoms, so a supplement form is your best bet. 

Naturopathic Tip: 

• For an extra boost of antioxidants, consider adding more berries, dark leafy greens, and colourful vegetables to your diet, in addition to taking resveratrol supplements. 

Vitamin D: The Sunshine Hormone 

Vitamin D plays multiple roles in the body, from bone health to immune regulation. In endometriosis, research shows that supplementing with vitamin D may help reduce pelvic pain and lower inflammatory markers, while also improving cholesterol levels. If you live in a region with limited sunlight (like Canada), deficiency is more common, especially in winter. 

Naturopathic Tip: 

• Get your vitamin D levels tested to see if you need more than a standard maintenance dose. Checking and optimizing levels is a crucial part of a comprehensive endometriosis plan. 

Vitamins C & E: The Antioxidant Duo 

Vitamin C and Vitamin E two of the most researched antioxidants for endometriosis. Together, they can help reduce pain (including pelvic, menstrual, and intercourse-related pain) and lower overall inflammation and oxidative stress. Think of them as complementary players that support each other’s antioxidant activity. 

Naturopathic Tip: 

• Increase your dietary sources of Vitamin C (like bell peppers and citrus fruits) and Vitamin E (found in nuts and seeds). Supplements can fill in any gaps to ensure consistent daily intake. 

Other Naturopathic Considerations 

• Diet: Following an anti-inflammatory eating plan (rich in vegetables, fruits, whole grains, and healthy fats) can help control endometriosis-related inflammation. 
• Stress Management: Chronic stress can worsen hormonal imbalances. Practices like yoga, meditation, or breathwork can help calm the nervous system. 
• Movement: Gentle to moderate exercise promotes blood flow, helps regulate hormone levels, and can ease stress. 
• Personalized Care: Because endometriosis presents differently in each individual, working with a qualified naturopathic doctor can help tailor a plan that fits your unique needs.

Final Thoughts 

Supplements can make a meaningful difference in managing endometriosis, but they work best as part of a holistic strategy. Supporting hormones, the liver, the immune system, and adopting a healthy and sustainable lifestyle all contribute to relief. If you’re considering any of these supplements, consult with a healthcare professional - especially if you’re on medication or have underlying conditions - to ensure safety and effectiveness. 

By combining these targeted supplements with personalized naturopathic care, you can tackle endometriosis from multiple angles and feel more empowered in your health journey. If you're looking for a personalized approach to managing endometriosis, book an appointment with Dr. Madison Sangster-Newbery, ND. Together, we can find the best plan for your body and health goals! 

Disclaimer: This blog post is for informational purposes only and is not medical advice. Always consult a qualified healthcare practitioner before making significant changes to your supplement routine. Everyone’s health picture is unique, and professional guidance ensures the best results. 

About the Author

Dr. Madison Sangster-Newbery, ND, is a licensed and registered naturopathic doctor based in Ontario. She blends evidence-based medicine with traditional naturopathic principles to support general health and athletic performance, focusing on optimizing recovery, endurance, and overall well-being. Inspired by her own health journey, Dr. Madison specializes in hormonal balance, stress management, and holistic care tailored to active, dynamic lifestyles. Passionate about helping others thrive, especially during demanding times like the holidays, she provides personalized tools and strategies for achieving vitality and balance. Outside the clinic, Dr. Madison enjoys exploring nature, staying active on the squash court, and cooking for friends and family.  

Dr. Madison Sangster-Newbery ND is currently licensed and registered to practice in Ontario under the College of Naturopaths of Ontario. She is a member of both the Ontario Association of Naturopathic Doctors and the Canadian Association of Naturopathic Doctors. 

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